Automatic speech analysis for the assessment of patients with predementia and Alzheimer’s disease

Automatic speech analysis for the assessment of patients with predementia and Alzheimer’s disease

“To evaluate the interest of using automatic speech analyses for the assessment of mild cognitive impairment (MCI) and early-stage Alzheimer’s disease (AD).

Healthy elderly control (HC) subjects and patients with MCI or AD were recorded while performing several short cognitive vocal tasks. The voice recordings were processed, and the first vocal markers were extracted using speech signal processing techniques. Second, the vocal markers were tested to assess their “power” to distinguish among HC, MCI, and AD. The second step included training automatic classifiers for detecting MCI and AD, using machine learning methods and testing the detection accuracy.

The classification accuracy of automatic audio analyses were as follows: between HCs and those with MCI, 79% ± 5%; between HCs and those with AD, 87% ± 3%; and between those with MCI and those with AD, 80% ± 5%, demonstrating its assessment utility.

Automatic speech analyses could be an additional objective assessment tool for elderly with cognitive decline.”

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Research Paper

König, A., Satt, A., Sorin, A., Hoory, R., Toledo-Ronen, O., Derreumaux, A., … & David, R. (2015). Automatic speech analysis for the assessment of patients with predementia and Alzheimer’s disease. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 1(1), 112-124.

Image Credit

“Nursing home” by Thomas Bjørkan – Own work. Licensed under CC BY-SA 3.0 via Commons – https://commons.wikimedia.org/wiki/File:Nursing_home.JPG#/media/File:Nursing_home.JPG

About the Author

jim.schwoebel
A biomedical engineer by training, Jim Schwoebel was educated at Georgia Tech. He is currently Co-Founder and Partner in NeuroLaunch, the world's first neuroscience accelerator, and Founder/CEO of NeuroLex.

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